USP Grade • ≥99% Purity (HPLC) • Third-Party Tested • Made in USA • cGMP Facility
Pharmaceutical-grade methylene blue reference standard. Independently verified for purity, identity, and heavy metals — every batch.
Pharmaceutical-Grade Purity
USP Reference Standard concentration. Verified ≥99% purity by HPLC against the United States Pharmacopeia methylene blue monograph. No filler dyes, no industrial binders, no surprises.
Triple-Verified Quality
Every batch is tested by an independent ISO-17025 accredited laboratory for identity, potency, heavy metals (Pb, Cd, As, Hg — all under 10 ppm), and microbial contaminants. The QR code on the label links to the Certificate of Analysis for your specific lot.
American Made, Transparently
Manufactured in an FDA-registered, cGMP-compliant facility in the United States. Our supply chain is documented from raw material to finished bottle — request the audit trail any time.
Concentration & Specifications
How Nutricel’s USP-grade solution compares to typical lab-supply methylene blue.
| Specification |
Nutricel 1% Solution |
Typical Lab Supply |
| Concentration |
1.00% w/v (exact USP) |
1% ± unspecified |
| Purity (HPLC) |
≥99% |
95–98% (often unstated) |
| Heavy metals |
<10 ppm (Pb, Cd, As, Hg) |
Not tested |
| Microbial limits |
USP <61> compliant |
Not specified |
| Solvent |
USP-grade purified water |
Tap or deionized (varies) |
| Reference standard |
USP Reference Standard |
Manufacturer’s internal |
| Certificate of Analysis |
Per batch, QR-linked |
Rarely available |
| Bottle |
UV-resistant amber glass |
Plastic / clear glass |
| Manufactured |
FDA-registered, cGMP, USA |
Often imported |
| Returns |
60-day, free |
Final sale common |
Specifications drawn from publicly available Certificate of Analysis. Comparison data from major lab-supply marketplaces, February 2026.
Concentration Reference
| Volume |
Methylene Blue |
| 1 drop (~50 µL) |
~0.5 mg |
| 5 drops (~250 µL) |
~2.5 mg |
| 10 drops (~500 µL) |
~5 mg |
| 20 drops (1 mL) |
10 mg |
| 40 drops (2 mL) |
20 mg |
| 1 fl oz (~30 mL) |
~300 mg |
| 4 fl oz (118 mL) |
~1180 mg total |
For research and laboratory reference. Drop volume varies by ~10% with viscosity and dropper angle. This product is not intended to diagnose, treat, cure, or prevent any disease.
Methylene Blue 1% Solution — Frequently Asked Questions
What is a methylene blue 1% solution?
A methylene blue 1% solution is a liquid formulation containing exactly 1.00% methylene blue by weight in volume — 10 mg per milliliter — dissolved in USP-grade water. The 1% concentration is a standard reference strength used in laboratory and research settings.
What does “USP grade” mean?
USP grade means the product meets the identity, purity, and potency specifications published in the United States Pharmacopeia monograph for methylene blue. Independent labs verify each batch against the USP Reference Standard using HPLC. USP grade is the benchmark used in pharmaceutical compounding and reference work.
How is the concentration verified?
Every lot is tested by an independent ISO-17025 accredited laboratory. The Certificate of Analysis reports concentration (target 1.00% w/v), purity (≥99% by HPLC), heavy metals (all under 10 ppm), and microbial limits. The QR code on the label links to the COA for your specific batch.
What are the bottle and dropper specs?
4 fluid ounces (118 mL) of solution in a UV-resistant amber-glass bottle with a 0.05 mL graduated glass-and-rubber dropper. Approximately 1180 mg of methylene blue total per bottle.
How should this product be stored?
Store at room temperature (20–25°C) in the original amber bottle, away from direct sunlight and heat sources. Keep tightly sealed. Methylene blue in solution is stable for at least 24 months when stored correctly. Do not freeze.
What is the shelf life?
Stamped expiration is 24 months from the manufacture date printed on the bottle. Stability is supported by accelerated and real-time studies on file with the manufacturer.
How is it shipped?
Each bottle is wrapped, padded, and shipped in a tamper-evident outer mailer with tracked carriers. Orders placed before 1pm ET typically ship the same business day; otherwise next business day.
Are there medications I should be aware of before using methylene blue?
Yes. Methylene blue is a known monoamine oxidase inhibitor (MAOI) and has documented serotonergic interactions. Before any use, review our Adverse Medications reference and consult a qualified healthcare professional. This product is sold for research and laboratory reference purposes; statements have not been evaluated by the FDA, and the product is not intended to diagnose, treat, cure, or prevent any disease.
